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KMID : 0377519910160000001
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Chung-Ang Journal of Medicine
1991 Volume.16 No. 0 p.1 ~ p.18
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Myocardial Ultrastructure in Ischemia
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Abstract
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Ischemic (or coronary) heart disease has focussed research on the pathophysiology of ischemia in i attempt to elucidate the various mechanisms behind the injury. Reversible injury is the most in-resting because cardiac tissue could be recovered by therapeutic measures such as delay of occur nce of myocardial necrosis and by reperfusion by thrombolysis or angioplasty. The ultrastructural aerations in organelles such as mitochondria, sarcolemma (myocardial cell membrane), sarcomere id nucleus, extracellular space and in microvessels can be used to determine the severity of injury experiments as well as in clinical field and can give detailed information about the actual injury
an
´>,y given time of biopsy removal. For this type of investigation transmission electron microscopy n useful tool because it not only identifies irreversible injury, but it also reveals different stages,
VTewrsible injury due to ischemia. .
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KEYWORD
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